Methadone: A Flicker Of Light In The Dark

Methadone: A Flicker Of Light In The Dark

To provide a better understanding of the very important role methadone plays in the treatment of addiction.
 
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 Methadone Vitamins

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chemenglala



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PostSubject: Re: Methadone Vitamins   Tue Apr 19, 2011 3:56 pm

For the constipation, my husband and i both take lactulose (i take 3 tbsp per day at night, he takes 2) and we have no problems with regularity at all! i go twice a day, the evening bowel movement is a little more solid and can be slightly difficult, but the mornings are a breeze! Has anyone else tried this?
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lilgirllost
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PostSubject: Re: Methadone Vitamins   Tue Apr 19, 2011 7:39 pm

I'm not sure what the active ingredient is in the lactulose you take, but I take a generic brand of MIRALAX and the active ingredient is Polyethylene Glycol. It works really well for the constipation. I have tried a lot of different laxative items and stool softeners and even the NUTRIDONE, but nothing helped. I even drank some Magnesium Sulfate, the entire bottle and all that did was give me HORRIBLE stomach cramps with little to show for all the trouble. This was the only thing I have found that works VERY well, doesn't cause gas pains and isn't too horrible to drink.


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PostSubject: Re: Methadone Vitamins   Wed Apr 20, 2011 1:35 am

I remember back when I ended up in the hospital for not being able to go. They gave me some Lactulose while there. It was really sweet and thick. It did help when I was in the hospital so I aksed my to doctor prescribed it for me.
I still use it every now and then for mild constipation, but when things get really tough, I usually have to resort to using an enema. Sad
Here is some information for some of you who might want to try it.




In the treatment of chronic constipation,[2] the metabolites of lactulose draw water into the bowel, causing a cathartic effect through osmotic action. Unlike other laxatives that are recommended for temporary relief, lactulose can be taken daily for decades.[3] It is safe for people of all ages, except for those in a very small percentage of the population that are galactose intolerant. Dosage may have to be adjusted over time to produce the desired effect because the laxative effect can decline with daily treatment.[citation needed]

In treating constipation lactulose works by increasing the water content and volume of the stools in the bowel, making them softer and easier to pass. Lactulose is made up of sugar molecules and is partly broken down by the bacteria that live in the lower part of the gut. This leads to the contents of the gut becoming more acidic because there are carboxylic acids among its metabolites, which are not absorbed from the lower bowel. That in turn causes water to be retained in the lower bowel. This increases the amount of water in the stools, softening them and making them easier to pass. The added volume of gas and flatulence caused by fermentation of the lactulose adds to the volume of the fecal material, and makes it easier to expel. The slightly acidic condition of the colon caused by the presence of acids causes active peristalsis. The combined effect of all of these processes relieves constipation in a very effective manner.

It is useful in treating people with chronic constipation due to forgetting or ignoring the need for defecation. The treatment is to start the dosage at a low amount and then gradually increase it over a period of weeks until the urgency is such that a daily bowel movement cannot possibly be ignored. After an efficacious dosage is determined, it is maintained indefinitely or increased as needed over time.

It is useful in treating people who abuse laxatives because lactulose has no toxic effect when taken at overdose levels, yet produces powerful results.

It is useful for negating the constipating effects of opiates and opioids, as in individuals who are on narcotic pain medication, are opioid dependent, or are receiving Opioid Replacement Therapy such as with methadone or buprenorphine for a previous opioid dependency. Lactulose is one of the most effective and easily tolerated medicines for this indication, it has been shown that it is not as well tolerated or as effective, in most cases, as polyethylene glycol 3350Da, a powder for solution (Miralax or Dulcolax Balance), which has a virtually non-existent rate of side-effects. In fact, taking one of these two medications along with lactulose has proven to be more effective in cases of stubborn, chronic constipation.

It is useful for treatment of hemorrhoids because it produces a soft bowel movement without any straining.

It is helpful for treating children who withhold their bowel movements out of fear because when taken in sufficient quantity and then withheld, it produces a very insistent, irresistible and powerful urge to defecate.[4]

It is considered a prebiotic because it enhances the beneficial bacterial flora of the intestine and is considered a digestive aid. [1]

It has an overly sweet taste that can be completely masked by mixing it with fruit juice or desserts. It can take 24 to 48 hours to work, but generally produces results within 4 hours if taken on a daily basis. It is best taken at breakfast along with a bowl of bran cereal.

In common with other osmotic laxatives, lactulose can cause electrolytic imbalances in sensitive individuals (see side effects below). However, lactulose tends to do this less because it does not rely on mineral salts to draw fluid into the intestinal tract and also because it relies on nonosmotic modes of action: It stimulates peristalsis through acidification and gas and increases feeling of urgency through enlarging the volume of the bowel contents.

It is sold over the counter (without prescription) in most countries in the world. In the United States and Austria, it requires a prescription over fears that it could be dangerous to diabetics. However, lactulose is an indigestible sugar and has been proved to be safe even for them. [The Annals of Pharmacotherapy: Vol. 26, No. 10, pp. 1277–1282.]

For the very few people who are galactose intolerant, Kristalose, a powdered form of lactulose that can be mixed with fluids, is manufactured almost free of galactose.

http://en.wikipedia.org/wiki/Lactulose


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